Gerard Byrne has exhibited at Documenta 13, 54th Venice Biennale, and at international biennials in Sydney, Gwangju, Lyon, and Istanbul amongst others. Recent solo exhibitions include the ACCA, Melbourne (2016), Kunstmuseum St. Gallen (2015), FRAC Pays de la Loire (2014), Whitechapel Gallery (2013), Renaissance Society, Chicago (2011). In 2007 he represented Ireland at the 52nd Venice Biennale. In 2006 he received the Paul Hamlyn award. He was Professor of Timebased Media at the Royal Danish Academy for Fine Art from 2007- 2016.

Byrne is represented by the Lisson Gallery in London, Kerlin Gallery in Dublin, and Nordenhake Gallery, Stockholm.